P-Shot PRP
For Men 40+
The P-Shot is an autologous platelet-rich plasma treatment designed for appropriately selected men experiencing changes in erectile function.
Maybe you can still get an erection, but it is not as firm as it used to be. Maybe maintaining it has become more difficult. Maybe blood pressure, diabetes, insulin resistance, weight, medications, hormones or simply getting older are becoming part of the equation.
PRP may be one option. It is not a miracle, and patient selection matters.
Start with why the erection changed.
Erectile function depends on vascular health, neurologic function, hormones, medications, metabolic health and psychological factors.
PRP should never become an excuse to ignore the underlying problem.
Built for a different stage of male sexual health.
Bolus generally reserves P-Shot treatment for men age 40 and older.
Less Firm
You can achieve an erection, but firmness is not what it used to be.
Harder To Maintain
You become erect but lose firmness sooner than expected.
Changing Health
Hypertension, diabetes, prediabetes, insulin resistance, excess weight, medications and vascular health can all intersect with erectile function.
Erectile function can be a health signal.
Changes in erections should not automatically be dismissed as aging. Erectile dysfunction can be associated with cardiovascular and metabolic disease. Appropriate evaluation matters.
Erection and desire are not the same thing.
I Want Sex - My Erection Is The Problem
This is the type of distinction that may make a regenerative erectile-function strategy worth discussing.
I Have Little Or No Desire
The P-Shot does not create sexual desire. Low libido can involve hormones, medications, sleep, psychological factors, relationships and other medical issues. If desire is the primary problem, the underlying cause deserves evaluation first.
Your blood. Your platelets. Concentrated.
PRP is prepared from a patient's own blood. Centrifugation separates and concentrates a platelet-rich fraction containing platelets and signaling proteins involved in normal tissue repair.
Assessment
We determine whether PRP is a reasonable pathway.
Blood Draw
A small amount of your own blood is collected.
PRP Preparation
The blood is processed to prepare platelet-rich plasma.
Treatment
After extensive local numbing, PRP is injected into selected penile tissues.
Think regenerative strategy - not instant erection medication.
Not Immediate
PRP is not intended to function like an on-demand ED medication. Studies generally evaluate outcomes over weeks and months.
Not Guaranteed
Some men report meaningful improvement. Others experience modest improvement or little noticeable change.
More Than One Treatment
Depending on the indication and response, additional treatment may be considered. There is currently no universally established P-Shot treatment schedule.
No miracle claims.
It Does Not Grow Your Penis
We do not promise permanent penile enlargement from PRP. Temporary fullness after injection should not be confused with permanent tissue enlargement.
It Does Not Create Libido
PRP does not create sexual desire or correct every cause of low libido.
It Does Not Stop Aging
Vascular, metabolic and hormonal health continue to change with age. Lifestyle and underlying health remain important.
Peyronie's disease and genital lichen sclerosus.
Peyronie's Disease
PRP has been investigated for Peyronie's disease, including protocols involving repeated treatments. Early research is encouraging in selected outcomes, but PRP should not be characterized as a proven cure or established first-line treatment.
Lichen Sclerosus
Autologous PRP has also been investigated as an adjunctive treatment for genital lichen sclerosus. The evidence remains limited, and patients require appropriate diagnosis, medical management and individualized assessment.
What does the evidence actually say?
PRP for erectile dysfunction remains an evolving area of research. Current studies do not justify guaranteeing improvement.
2026 Systematic Review and Meta-analysis
Seven randomized trials involving 479 patients found no overall difference between platelet-rich therapies and placebo in combined IIEF outcomes at 1, 3 or 6 months. A possible six-month clinically meaningful response signal was based on fewer studies and requires cautious interpretation.
READ THE STUDY2026 Meta-analysis of Randomized Trials
Another contemporary meta-analysis evaluated randomized trials of intracavernosal PRP for erectile dysfunction, illustrating why this remains an active area of investigation rather than settled therapy.
READ THE STUDYQuestions men actually ask.
Does the P-Shot make my penis bigger?
No permanent enlargement should be promised. Some patients may perceive temporary fullness or changes in tissue quality, but this is not a penile enlargement procedure.
Does the P-Shot increase libido?
No. Desire and erectile function are different. If low desire is the primary issue, evaluation of possible hormonal, medication-related, psychological, relationship or other medical contributors is more appropriate.
Does it hurt?
We use extensive local anesthetic techniques to make the procedure as comfortable as reasonably possible. Pressure, brief pinching, tenderness or temporary sensitivity can still occur.
How quickly will I see results?
This is not an on-demand ED medication. Changes, when they occur, may evolve over weeks to months. Response varies considerably between patients.
Will I need more than one P-Shot?
Possibly. Some patients may be considered for additional treatment based on indication, response and clinical assessment. There is no universally established PRP protocol for erectile dysfunction.
Can P-Shot treat Peyronie's disease?
PRP is being investigated for Peyronie's disease, but current evidence is not sufficient to call it a proven cure or established first-line treatment. Peyronie's disease warrants appropriate clinical evaluation.
Do you treat men under 40?
Bolus generally reserves P-Shot treatment for men age 40 and older. Erectile dysfunction in younger men deserves appropriate evaluation for vascular, endocrine, medication-related, neurologic, psychological and other potential causes rather than automatically proceeding with PRP.
Do you accept insurance?
No. Bolus Med Spa does not accept or bill insurance. HSA and FSA cards may be accepted when permitted by the patient's plan. Bolus does not complete prior authorizations or reimbursement paperwork. Applicable coded receipts may be provided when appropriate. Custom letters, forms, emails or administrative correspondence are subject to a $50 administrative fee.
The goal is not to sell you a P-Shot.
The goal is to understand what changed, determine whether PRP makes sense and identify when something else deserves attention first.
